Seymour Duncan is one of the finer choices. I've had EMG's for a while, active and passive. Then I got an LTD MH-1000nt that came with Seymour Duncan JB's. Awesome Pickups, very very versatile. So those are a great choice. I also just ordered a Nazgul bridge and Sentient neck for my 7 string. They make 6 string versions as well. Will give a very good metal sound with distortion, meanwhile the sentient neck pickup sounds beautiful with cleans. As with that being said. JB's or nazgul and sentient in my opinion. Dimarzio deactivator X as well, I forgot I have one of those in my Oktober Annihilator. I went through a lot of different pickups, those are the nicest I've heard. But note, you wont really hear the difference through the vypyr like others mentioned.