which one would be the best selection for a Squire Strat of a versatile guitarist playing from blues rock, hard rock to new age, even some heavy stuff .

1. Fender Hot Noiseless pickup set
2. Fender Custom Shop '69 Strat Pickup set
3. Seymour Duncan Everything Axe Single Coil Set
4. SHR(bridge) SCR(neck) SVR(middle)

-Ibanez Jem 7V
-Fender Squire Strat
-Pod X3 Live
-Marshall AVT

p/s: pardon my english.. i am not a native.
have you listened to any sound demos of the pickups?
I reccomend you do...
But remember making a guitar sound better is not going to help it play better so if you don't like the feel of it don't bother changing pickups
i just saw a demo of the Seymour Duncan everything axe on youtube.. that was awesome!
the guitar feels ok.. the neck is fast, the action is good but the problem is, the stock pickups have become pretty old and kind of muddy sounding.. that's why i was planing on replacing the pickups.