Hi this may sound ultra noobish but what products do you purchase to connect your guitar to a Amplitube/Amlitube-esque program?
There are alllll kinds of ways, from a $3 adapter at radio shack to a multi-thousand dollar interface. I was just using my Mbox Mini with amplitube a few minutes ago, but ended up having to remove amplitube from my track because it was making obnoxious background sounds. Stupid 'LE' programs.

Anyway, back to you- search 'usb interface' on musiciansfriend and pick something you like there. That's the easiest way to do it.
Telecaster - SG - Jaguar
Princeton Reverb, Extra Reverb
P-Bass - Mustang Bass
Apogee Duet 2 - Ableton Suite
I use a 1/4th to 1/8th adapter to my line in for amplitube while using the asio4all drivers

clear and no lag. only thing is if i want to record I have to put the speaker port on my desktop to the line in on my laptop and record on that.

USB would be easier but the adapter is like 2 bucks