What is the difference between regular and f-spaced pups?
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its the pole spacing


It's the spacing for a Fender guitar or a guitar with a Floyd Rose.
Quote by zakkwyldefan79
F-Spaced pickups are for Fender guitars, guitars with Floyd Rose trems or similar trems and most import guitars with TOM bridges such as Epiphone, LTD, Dean and many others.

This is true. My Epi LP (which has a TOM import version) has string spacing of 2 1/16... that, IMO, is not normal spacing.
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You CAN play anything with anything....but some guitars sound right for some things, and not for others. Single coils sound retarded for metal, though those who are apeshit about harpsichord probably beg to differ.