So i got this new PRS Ce 22... I am wondering if i take out the stock pickups and put in a different one, am i still going to be able to use the 5 way rotary switch to coil split?


if the pickups are 4 conductor, yes. if not it's gunna take some work.
i used to be a mod, then i took an arrow in the knee.
You have to buy four-conductor (pretty normal for after-market pups) and wire the switch. If you know what the wires are for old ones (hot, ground, etc), it shouldnt be a problem; otherwise, find a wiring diagram some place for a 5-way.