#2
I would say bridge. Neck position is more creamy, this doesn't sound softer.
Gear:
-Gibson Les Paul Studio Cherry Sunburst w/ Alnico Pro II
-1960 Yamaha Orange Sticker Acoustic
-Marshall JCM2000 DSL 401
-Fender Hot Rod Deluxe
-Blackstar HT-5RH
#3
Why don't you use your own ears and tell what's best for the song? Much easier and much faster than asking a forum.

Step 1) Listen to the song
Step 2) Play the song on your guitar in each pickup position
Step 3) Find out what sounds best

Congratulations. You are done.
Gear
Warmoth Stratocaster
Jackson KE3
ESP LTD EC-256

Bogner Alchemist 2x12
Vox AD30VT

Gator GPT-PWR Pedalboard
MXR CAE MC-404 Wah
BBE Boosta Grande
Korg Pitchblack Tuner
Digitech Bad Monkey
Line 6 Uber Metal