#4
Are talking about the pick gaurd or the actual pup cavity in the wood? It's a Squier so there shouldn't be any problem. Even there was a problem, which I highly doubt, it wouldn't be too hard to route out the cavity or trim the pick gaurd. Do you own a Duo Sonic?

You could always measure the slot and then compare it to the specs of the Fender pup you want, which is which pup?