Is there a setup where you can have your keyboard and sampler running off the same midi clock and a tap tempo funtion at your disposal?
In that instance, I'd use Ableton Live as my sampler and keyboard sound source so everything would be synchronized. That's how I'd personally do it, so it is possible.
Telecaster - SG - Jaguar
Princeton Reverb, Extra Reverb
P-Bass - Mustang Bass
Apogee Duet 2 - Ableton Suite