So Im in the process of finding an Ibanez RG550 on Ebay.

The amp i have is a Peavey Vypyr 30w.

I was thinking of changing out the pickups and putting in an

Air Norton in the neck and a Tone Zone in the bridge.

So question is with that type of amp would changing the pickups

have any effect at all? Or is the amp going to make my guitar sound like

$199 no matter what im using?
The tone of your guitar would indeed change to reflect the new pickups however it will not change the tone of the amp.

I generally see pickups as a good upgrade on all guitars as they are easy enough to chuck in a new guitar when you upgrade but in this case it sounds as if you have a problem with the sound your amp produces and if this is the case pickups wont help in the long run.
ESP M-1 - Dimarzio Super3
Ibanez RG3270 ToneZone/Blue Velvet/Paf Pro
Ibanez RG1527
Mercer Blackmachine Replica

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TC GMajor

Gain Wh0re and Diezel Mafioso