I really like the deep rumbling guitars like in some of the Black Keys' and Jimi Hendrix's stuff.
Marc Ford & The Neptune Blues Club
The Steepwater Band
The ARC Angels
Hot Tuna
Alvin Youngblood Hart
The Allman Brothers Band
Doyle Bramhall II
Back Door Slam
Canned Heat
Capt. Soularcat
Delta Moon
Devon Allman's Honeytribe
Fleetwood Mac (The original line-up)
Paul Butterfield Blues Band
Gov't Mule
Hill Country Revue
North Mississippi Allstars
Joe Bonamassa
Joe Pitts
John Mayall
Johnny Winter
Sonny Landreth
Susan Tedeschi
Tab Benoit

The bolded selections have some beefy and nasty guitar tones and/or a heavy Jimi Hendrix influence. Happy hunting.
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Quote by Weaponized
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The Black Keys. There are more than blues classic rock, but they still have a great sound of rock with heavy blues influences.

In addition, widespread panic has some songs (some in the album "Is not Life Grand") that have a good sense of sadness.

You can never go wrong with The Jimi Hendrix Experience or (his solo work too.) Electric Ladyland is one of my favorite albums.
Source (s):
To listen to good music for a couple of decades.