Looking at getting a mesa cab, but I can't afford to spend $1000 on the 4x12, so for half that on the used market, I'm looking at 2x12s. What exactly is the difference between the two? Would it be able to keep up with a 4x12 in a band setting?
Kodiak bears make awesome bandmates.

Quote by wolvenrick
no seriously 7x NGD is epicness i declare you the winner of all NGD's on UG never have i seen this xD
The cab size has virtually no effect on the volume it produces.

Bigger cabs tend to sound "fuller" though.
Everyone is entitled to an opinion.

Feel free to express yours so I can make an informed judgement about how stupid you are.
2x12s are equally as loud as 4x12s. They also tend to sound tighter due to the small space, less speakers moving.

4x12s have more bass because of the larger cabinet enclosure.

Get a 2x12 - much easier to move/lighter and cheaper. Unless you really just want the visual of a 4x12 on stage.