Is it common to use multiple guitars for one song (if so, how to replicate that live)

Something like...

-My fixed bridge Explorer for riffing.

-one of my Floyd Rose guitars for soloing so that I can make use of using the tremolo

-My 7-string for some low riffing

-and maybe even my Strat for its characteristic tone during certain parts

I would think that studio recording people would do stuff like this to record the most optimal thing possible, but then how do you go about playing it in a live setting if it used so many different guitars?