I've been looking around for the best way to get the best distortion out of my guitar and amp, but I need some suggestions. I have a Gretsch G5120 with stock pickups, and a Vox AC30 CC.

The sound I try to play closest to are like these



I realize I probably can't get those sounds exact with what I have now, but are there any pedals or pickups I can get to get a solid, well rounded distortion out of a hollow body guitar and vox amp?

The best I have tried is SolidGoldFX's SuperDrive... this distortion is an extension of your sound... it will no color your tone, but supercharge it, as though you modded your amp and pickups. I can't recommend it enough!
You should be able to get close enough to those sounds with your current rig. Not sure exactly which guitar parts you're going for, but I would look into some overdrive or light distortion pedals first. That should get you closer to the parts with a bit of crunch. For the Goo Goo Dolls song, there are some guitar parts where I hear a clean guitar with some other effects, maybe chorus and delay.
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Try a treble booster. Brian May uses one.
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