#1
Hello pit, i have ventured here today to ask and see if this is a justified thought by a caring great-grandson or not.

Well, my great-grandmother who pretty much took care of me and raised me until i was around 6, has now developed Alzheimer's disease. I am also the first grandchild in the family and she loved and cared about me more than my cousins. We first found out about a year and a half ago. I care about her so much, but it's so hard visiting her now because half the time she doesn't know my name, or my grandmother's(who is taking care of her) and she is always saying "when are we going home to see my baby?" even though she is at home. This is just the tip of the iceberg, but let's get to the real point.

I am a legal medical marijuana patient in Michigan, something my mother and grandmother are extremely against. (they are religious) I have done extensive research on the herb and have read that cannabis prevents deposits in the brain that are associated with Alzheimer's as well as prevent an enzyme called acetylcholinesterase from accelerating the formation of "plaques" and blocks clumps of protein that can inhibit memory and cognition in Alzheimer’s patients.

I am tired of seeing them give her these government approved synthetic bullshit drugs that honestly, don't even ****ing work. She's actually getting worse. I want to help her, i want her to be the loving person she once was, not the state of delusion/delirium she is currently in. The thing is, how should i come about telling my mom/grandma about this? Is it right that I want to give her some edibles/extracts/THC pills? I know the second i bring it up they will immediately shoot me down and call me full of bullshit.
#2
I'd say at this point, the weed won't do anything. In fact, due to the fact she is taking Alzheimer's medicine, it might have a bad mix in her brain, especially since it's damaged.

Sorry bro.

I've lost several of my family members to Alzheimer's, and it never gets easier, but you just try to be supportive of yourself and your family.
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#4
Well normally drugs are bad m'kay, but it's probably worth a shot in this situation.
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#6
Make sure you give it to her legally it's not worth going to jail/prison for. But honestly? No ****ing different than selling liquor for a toothache right?
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#7
Quote by dig up my date
I have done extensive research on the herb and have read that cannabis prevents deposits in the brain that are associated with Alzheimer's as well as prevent an enzyme called acetylcholinesterase from accelerating the formation of "plaques" and blocks clumps of protein that can inhibit memory and cognition in Alzheimer’s patients.


What you mean to say is that you've done biased research to prove your point. Cannabinoids inhibit neurotransmitter release at presynaptic neurons in a fairly general way. This is where the "high" comes from. Your brain needs to maintain regular levels of neurotransmission for proper function, so in all honesty, the risks of messing with that normal brain function far outweigh the benefits. I imagine that a patient with Alzheimer's disease, who already has abnormal brain function, doesn't need her brain chemistry messed with even more.

I don't doubt that scientists have shown evidence of the benefits you're stating, but it's pretty easy to prove what you want to prove in a test tube. If it really was that great of an idea, people all over the world would be using cannabis to treat Alzheimer's and other cognitive syndromes. This just isn't the case. In fact, cannabis use can result in cognitive decline and can even exacerbate symptoms of mental illnesses like schizophrenia, which also have cognitive components. Patients with neurodegenerative diseases can develop psychosis-like symptoms at later stages, so why would you want to give them an agent that could exacerbate this?

The drugs that they're giving her, which I'm sure come with some pretty bad side effects themselves, are going to be way better for her than pot, I can assure you. Any drug that gets onto the market has to go through a battery of preclinical animal and clinical human trials of safety and efficacy before it's approved for general use. She's probably seeing a neurologist or some sort of specialist who has done more "extensive research" on the topic than you have, and knows how the disease and these drugs work much better than you do. Let the doctors do their job.
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#8
Quote by Jimmy_Page_Zep
What you mean to say is that you've done biased research to prove your point. Cannabinoids inhibit neurotransmitter release at presynaptic neurons in a fairly general way. This is where the "high" comes from. Your brain needs to maintain regular levels of neurotransmission for proper function, so in all honesty, the risks of messing with that normal brain function far outweigh the benefits. I imagine that a patient with Alzheimer's disease, who already has abnormal brain function, doesn't need her brain chemistry messed with even more.

I don't doubt that scientists have shown evidence of the benefits you're stating, but it's pretty easy to prove what you want to prove in a test tube. If it really was that great of an idea, people all over the world would be using cannabis to treat Alzheimer's and other cognitive syndromes. This just isn't the case. In fact, cannabis use can result in cognitive decline and can even exacerbate symptoms of mental illnesses like schizophrenia, which also have cognitive components. Patients with neurodegenerative diseases can develop psychosis-like symptoms at later stages, so why would you want to give them an agent that could exacerbate this?

The drugs that they're giving her, which I'm sure come with some pretty bad side effects themselves, are going to be way better for her than pot, I can assure you. Any drug that gets onto the market has to go through a battery of preclinical animal and clinical human trials of safety and efficacy before it's approved for general use. She's probably seeing a neurologist or some sort of specialist who has done more "extensive research" on the topic than you have, and knows how the disease and these drugs work much better than you do. Let the doctors do their job.


Like I said, just said much more eloquently and in much more detail.
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#9
Extensive research, aka read some things on wikipedia, NORML, and various websites. While never setting foot in a lab or wrote a thesis.
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#11
Quote by Junglie
Give her a dose of ALZ-112.





Haha.


But honestly, it could damage her further, but if you really want to give it a try, I say do it. I would probably do the same exact thing.
#12
Quote by Steve635z
But if you give her some she'll forget to take them....


I now understand everything in your sig..

OT..I'm really sorry man..And I honestly don't know exactly what to say.

Firt of all, you should talk to a professional and inquire and find out if mixing the things will be worse, or make any diference at all.

As to your parents..I don't know, if you speak to someone who knows his stuff, try and set up a meeting with you, this person, and your parents and try and have a serious discussion about it..
Never imagine yourself not to be otherwise than what it might appear to others that what you were or might have been was not otherwise than what you had been would have appeared to them to be otherwise
#13
Quote by metallica #1

Haha.

But honestly, it could damage her further, but if you really want to give it a try, I say do it. I would probably do the same exact thing.


He'd just have to develop a more aggressive virus strain.
#15
Quote by Junglie
Give her a dose of ALZ-112.


I love you.
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How was Confucius death metal?
You've clearly never read any Confuscius.

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#16
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Except it might start a pandemic from it.

What's the worst that could happen?

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#17
Quote by blackthought
What the **** do doctors know? It's not like they have special schools for medicine and shit.

#18
Quote by Junglie
Give her a dose of ALZ-112.



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#19
Quote by Jimmy_Page_Zep
I don't doubt that scientists have shown evidence of the benefits you're stating, but it's pretty easy to prove what you want to prove in a test tube. If it really was that great of an idea, people all over the world would be using cannabis to treat Alzheimer's and other cognitive syndromes.
Unfortunately this isn't the case. While I'm not recommending anyone use pot to treat Alzheimer's, I do think that anyone with a cronic non-curable illness should research as many alternative cures as they can.

The fact is the govt suppresses information in an attempt to keep anyone from making claims related to the health benefits of a commercial product. This has gone as far as the FDA calling walnuts and cherries illegal drugs when the researched and well known health benefits of their nutrients are cited by the producer. It costs between $3/4 to 1.5 million in fees to the FDA to have a claim and associated research reviewed. This means that there will never be a commercially produced product that has beneficial heath claims produced unless a patent is involved.
#21
Quote by fly135
Unfortunately this isn't the case. While I'm not recommending anyone use pot to treat Alzheimer's, I do think that anyone with a cronic non-curable illness should research as many alternative cures as they can.


I'm all for living a healthy, active lifestyle instead of relying on prescription medications. However, there are definitely situations when prescription pharmaceuticals can be beneficial, and Alzheimer's is definitely one of those cases. Although we'll probably never know everything about the subject, we've come a long way in brain research. There are treatment plans that combine pharmaceuticals and cognitive therapies (problem-solving games and puzzles, for example) that have been shown to slow neurodegeneration. Alzheimer's is a terrible disease and I am truly sorry for TS's situation. I agree entirely that his family should research as many treatments as possible, although I don't think for a disease like Alzheimer's you can really call any of them "cures". My point is that in this case, as you and I have both stated, TS should NOT interfere with his family member's treatment by administering pot.

You also said:

Quote by fly135
there will never be a commercially produced product that has beneficial heath claims produced unless a patent is involved.


This is true, but health care is a business just like any other. It all comes down to money. I don't necessarily agree with the way it's run, but it is what it is. But just because it's driven by money doesn't mean that the treatments don't work...
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#22
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Blood will be sneezed, fevers, and people will die. Ehh not a big deal.


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#23
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What's the worst that could happen?


Thanks


Yay I got sigged
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How was Confucius death metal?
You've clearly never read any Confuscius.

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#25
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Lucky bastards.


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#26
Quote by Jimmy_Page_Zep
This is true, but health care is a business just like any other. It all comes down to money. I don't necessarily agree with the way it's run, but it is what it is. But just because it's driven by money doesn't mean that the treatments don't work...
I think that it's an infringment of our rights and an enormous deception on the public and profiteering enabled by strict govt control. I would prefer less draconian restraints on the market than we have now.

This is a huge subject and unless you've had experience with people who have or had mystery diseases normally called syndromes but have had sucess with alternative cures, then it's not something easily understood. Most people feel that the govt protects us from "snake oil" salesmen, but IMO it has done as much damage as it has protection. The govt has virtually eliminated the huge body of anecdotal research of alternative medicine that the public could contribute to and benefit from by demonizing anything that doesn't come from a major pharmaceutical. Even to the extent of calling walnuts an illegal drug.

http://www.fda.gov/iceci/enforcementactions/warningletters/ucm202825.htm

Because of these intended uses, your walnut products are drugs within the meaning of section 201 (g)(1)(B) of the Act [21 U.S.C. § 321(g)(B)].
#27
Quote by fly135
Even to the extent of calling walnuts an illegal drug.

http://www.fda.gov/iceci/enforcementactions/warningletters/ucm202825.htm


Your link doesn't say anywhere that walnuts are "an illegal drug". It was just a warning to a company that sells walnuts about how they marketed their product. The company violated the Federal Food, Drug, and Cosmetic Act by making unauthorized claims about the potential benefits of eating their walnuts. So the FDA gave them a warning. Seems fair to me.

Based on claims made on your firm's website, we have determined that your walnut products are promoted for conditions that cause them to be drugs because these products are intended for use in the prevention, mitigation, and treatment of disease


Obviously walnuts are healthy (in moderation), but the company was overstating their product's potential health benefits. The claims they were making, which are presented in your link, would require FDA approval prior to including them in their marketing plan. Makes sense to me that the Food and Drug Administration governs what claims can be made about the health of food. It wouldn't be fair for KFC to make claims that chicken is a healthy meat when they batter and deep fry any nutritional value out of it. At the end of the warning letter, the FDA even gives them a chance to remove the claims:

You should take prompt action to correct these violations. Failure to do so may result in regulatory action without further notice. Such action may include, but is not limited to, seizure or injunction.
Please respond in writing within 15 working days from your receipt of this letter. Your response should outline the specific actions you are taking to correct these violations and to prevent similar violations. You should include in your response documentation such as revised labels or other useful information that would assist us in evaluating your corrections. If you cannot complete all corrections before you respond, we expect that you will explain the reason for the delay and state when you will correct any remaining violations.


Like I said previously, I don't necessarily agree with every aspect of the way the health care system or big pharma are run, but I think you're being far too paranoid. I've spent the last 2 years studying and developing new treatments for schizophrenia. In that time I've dealt with countless fellow grad students, scientists, physicians, and several pharmaceutical companies. There are people out there only looking to make money, but people generally enter this field because they enjoy it and they want to improve patient lives. That's been my experience, anyways.
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#28
I'm unsure, drugs are good but sometimes you have to let nature take it's course. she sounds like she's too far gone but I give you all the love I have man. I hope you can make it through this.
#29
Try consulting with a doctor or someone with ACTUAL MEDICAL KNOWLEDGE before you just start giving weed to someone on med's, you don't know what can happen and i doubt you wanna be the one to make it 10x worse.

I feel bad for you though, i can't imagine how bad it has to be to have to go through that as a family
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