I play in a quasi progressive rock band that has heavy and bright parts along with lots of clean mellow parts

So basically I need that nice meaty chunk (not deathcore chunk levels) along with fluidy clear cleans.

I was a SC250 pickups in my PRS Custom 24 (through an uberschall) and have the original 58/08's and was thinking about keeping the SC250 bridge pickup in but replacing the neck SC250 with the 58/08 for more fluidy sounds.

thoughts? or would you guys recommend other pickups? I was also thinking about swapping the SC250 for bareknuckles (but damn they are expensive!).

I've already had to tweak the amp EQ and slap a MXR 10 band in order to take some of the sterility out of the clean channel.
Current Gear

Bogner Uberschall
Mesa Dual Rectifier (Old Version)
Orange Closed Back 2x12 Cab with V30's
PRS Custom 24 Top 10 with 57/08 pickups
Schecter Hellraiser
Breedlove Atlas AD20
A bunch of pedals
Spin 'round carousel when your horse isn't screwed in.

My band:
Fractured Instinct
(For fans of Death/Groove/Prog Metal)

Ibanez RGA42E
Ibanez S420
LTD H-301
Ibanez RG520
Peavey Predator USA
Douglas Grendel 725
Line 6 Pod HD500X