So I bought a Dragonfire Screamer and two Strat noiseless single coils to replace the pups in my Ibanez. I've figured out how to wire it for it to have the same functions, but I want to try something different, if it's possible. I never use the bridge+mid position, is there a way to wire it up where the second position is essentially a killswitch? If it matters, it's a five way switch with 8 lugs (Or whatever they're called) in a straight line.

Also since I'm restringing the guitar as well, the Gibraltar standard bridge has the option of string through the body or string through the back of the bridge (TOM style). Would there be any significant change in tone between the two options?
RG351DX - Bridge Dragonfire Screamer, Mid+Neck Fender Hot Noiseless
Peavey Valveking 112 - Eminence GB128
AMT E1 > Joyo AC Tone > Dan'o EQ > Shimverb > Digidelay