Hello guys,

I'm having a problem with my yamaha guitar. I have already set the correct intonation of this guitar. When I pluck/play the open E string, it is in tune. But when I fret the E string on the 10th fret(other frets) it is detuned. Same goes for the B string.

Thank you so much for the help.
I think I added you to friends, first of all. If I didn't add me to friends. Second, this is something that needs to be done by someone that has some experience. Ask around your local guitar shop for the guitar tech in your area.
If your action is too high you could be going out of tune, due to the amount of string movement when fretted.
How can you say that you set intonation right, when it is obviously wrong? You need to move the saddle closed to your pickups.