Hey Acoustic and Classical Guitar forum!
I've recently gotten myself an acoustic guitar, and am wondering if switching between standard and open E tuning will affect the intonation on my guitar? If so, will it be an unbearable difference?
Do you guys fix the intonation after every time you change tunings?
we play our guitars and tune them in a variety of tunings without having our guitars re-intonated.
Quote by Skeet UK
I just looked in my Oxford English Dictionary and under "Acoustic Guitar", there was your Avatar and an email address!
Intonation is a function of the placement of the frets and the distance between nut and saddle.
If that is all correct, then no amount of string changing should have any effect.

What can have an effect is excessively high action. When the action is too high at the upper frets, then the act of pushing the string down to the fret will "pull it sharp", even if the intonation is set properly.