#1
in the 2:50 min of this: http://www.youtube.com/watch?v=wDFkkqmhclw interview John talks (more like a mumble) and he sounds super weird. In fact, i dont remember hearing him talking normal in any other video. Whats up with that? Is this what drugs do to you - or hes just super shy that everything comes out as a mumble?
#2
He was always something of a mumbler, not big on interviews, not comfortable in the spotlight etc. In 1999 he would have been fairly fresh out of rehab and having all of his teeth replaced after an addiction-related infection. So he was probably not the most talkative guy in the world at the time of this interview. Some of his mid-90s heroin phase interviews were so bad they had to be subtitled.

His speech has gotten progressively better, he's still quiet but you can understand him just fine in more recent interviews.