#1
I have a strat with single coils and I was thinking of upgrading to Seymore Duncan hotrails to play pop punk like Greenday, The offspring, NOFX etc.

Will these be a good choice? I dont have the option of a humbucker guitar.
#2
If your amp is decent, then it will do the trick (thought it might have a bit too much output, I'd go with the JB jr).
Charvel So-Cal (SH6TB/N, killswitch), Jackson RR5FR (TB6/Jazz, Drop C). Joyo pxl pro.
Loop1=Crybaby from hell, Boss PS-5, Seymour Duncan 805 or Green Rhino, EQD Hoof or Earthbound Audio Super Collider. Loop 1 into ISP Decimator II.
Loop 2 (FX loop)-Line6 M9, TC Spark Mini. Loop 2 into mxr 10band. All into a Peavey Triple XXX 212, Ibanez IL15.