I hope this is the right place...

I was adjusting my strings yesterday so I removed the neck (this is my Les Paul Special) and did what I needed to do. The problem is, after returning the neck, my low E is insanely loose and unplayable, and the rest are also loose but at least I can get to make a sound.

How could I fix this? Should I take it in to a guitar shop (I'd rather not if it's possible to fix on my own)?

PS: If pictures would help I'll gladly supply some.
Could you explain a little better on what exactly you did and what you were trying to accomplish?
What do you mean you was adjusting the strings? Have you tuned the guitar again as you say the strings are loose?