Two totally different guitars with different sounds. Depends what you are looking for. The Strat is a solid body with single coil humbuckers and a bolt on neck with a trem. The Epiphone Dot is a semi-hollow body with a set neck and humbuckers. Two completely different but nice guitars. Personally given the choice since I play a very wide variety of styles, I want the Epihone for a gig but that's just me.