I'd like to buy NI Komplete Audio 6 interface. What would be the best way to connect Line6 DL4 delay to it? Is there any other way than this:
guitar -> DL4 -> KA6

KA comes with Guitar Rig, so there will be some amp/speaker sim.

Or maybe it is better to connect DL4 through amp and use Guitar Rig column simulator?
guitar -> amp -> DL4 -> KA6
My current amp does not have fx loop.

What would be the best way to do that?

Thanks for answers,
I'd like to record and be able to use DL4 knobs live.
I'm not sure I understand Your second post. Can I record with pedal and later use software amp?