I have a guitar with emg 81/85s that I use on a tube amp. I've heard very often that actives are horrid on solid state amps although I haven't tried in myself. Currently however, I record guitar on reaper and have recently downloaded bias fx as a plugin for my amp. My question is, do amp sims work with actives? Might be a completely stupid question but I really don't know.
No issues unless your audio interface preamp is too hot and clips.
Mine works well, so should yours if everything is well set up