Ive just got one, anyone got any good setting for one? Or for any delay pedal for that matter, Im sure it'll be kinda simular to other boss delays.

Im after a good sound for solo's, not to harsh.

Also, Im unsure wether it'll be better to put it in the FX loop or in front of my 5150 and what benefits each one has?

Use a short delay time, with feedback to about 4 notes, and effects level about medium level, that's a nice delay for solos.
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Fender Strat/Tokai LS80>few pedals>Orange Rocker 30