are pinch harmonics easier to make on higher or lower gauge strings?
Quote by Seryaph
You need to douse it in a 20/30/50 ratio of mustard/ketchup/horseradish and stroke it as fast as you can untill the mayonaise squirts out. Then consume.
from my experience it doesnt matter, rite now im using 42' gauge mostly, its easy to pull off pretty much on any string except the 1st string (before the 8-9th fret) but that's like super thin

i used to use 52 guage a while back, same thing, it wasn't an easier or harder

what kind of pickups are you using?
i think it depends on your pickups natural harmonic response, not strings
Agile AL-3000 Cherry Sunburst
Fender American Strat HSS
1981 Yamaha FG-335II
Crate V1512 (USA made)
Fender Frontman 15R
Dunlop Crybaby Slash Wah
MXR EVH Phase 90
Ibanez TS9 w/ Keeley Baked Mod
Boss SD-1
Boss DD-3
from my experence its the same no matter what gauge your strings are, but if you have bigger strings i have noticed that you get a little fatter of a sound.... like Zakk Wyled style
i'd say it works better with 9's on drop B 12's give a flatter sound which looses the effect, but then again it mainly depends on your pickups i find it easier with a duel double coil pickup like BDSM for example