#1
I need help on improving my tone, I want to polish it off so it is the best it can be with the gear I have.

Gear: Ibanez S470, with the stock pick ups, Peavey JSX head and Marshall 1960V cab, Morley Bad Horsie Wah.

Genre: Hardcore/metal/shred (heavy palm muted drop tuned rffs, searing solos)
Budget: 400$ (American currency)

Question: Do you think replacing those stock pick ups with a D-sonic and Breed combo would make a huge difference in my tone, or would it be better to buy a couple of pedals (if so, which ones?)?
What other suggestions do you have that can improve my tone?

Thanks in advance!
Main rig:
ESP Horizon FR-II
ENGL Invader 150
Mesa Traditional cab w/ v30's
ISP Decimator Pro Rack G
BBE Sonic Maximizer 482i

Back up rig:
ESP Eclipse STBC
LTD EC-1000 VB
Framus Cobra modded
#2
"Pick ups are the cherry on top.".I stole that line from one of the stickied threads.

I'll suggest any dimarzios, as they seem to go great with ibanez's. If I got the D-sonic for the bridge i'd put the rail nearest the bridge, as it's apparently better for rhythm. Rail towards the neck for leads, but i find i use the neck for leads. You might also consider an Air Norton for the neck.

but if you want pedals, an Overdrive and a chorus are useful basics. Maybe a delay

I am liking your current set up btw.
2005 Ibanez RG1570
1998 Ibanez RG7620
1998 Mesa 2 Ch. Dual Rec
#3
I'd say pickups, and maybe an ISP decimator? and a delay pedal, if you play solos.
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#5
Delay and phaser are my favourite effects actually, can you suggest some good pedals?
Main rig:
ESP Horizon FR-II
ENGL Invader 150
Mesa Traditional cab w/ v30's
ISP Decimator Pro Rack G
BBE Sonic Maximizer 482i

Back up rig:
ESP Eclipse STBC
LTD EC-1000 VB
Framus Cobra modded