I had perfectly fine callouses (sp?) on my fingertips until a few days ago.

In my opinion, I don't think I upped my amount of time playing, but now my fingers are shredded. It's frankly disgusting.

Anyway I can stop this, or treat it?

I'm not sure about it but it's happened to me before. They get better after a couple of days.
Quote by Skwisgaar Skwigelf
Fish don't gots no good metal to listens to.
my fingers seem to shed the skin on my callouses.
they did last night and it nacks when i play.
i still do ofcourse.
i used to have the problem getting blisters from playing too much even though i had calluses, but from carrying on regardless i've stopped getting them. It took over a year for my fingers to get used to it, now i just get skin peeling off a little and slightly sore fingers but nothing that effects my playing.
Rig Winter 2017:

Fender Jazzmaster/Yamaha SG1000
Boss TU-3, DS-2, CS-3, EHX small stone, Danelectro delay
Laney VC30-112 with G12H30 speaker, or Session Rockette 30 for smaller gigs
Elixir Nanoweb 11-49 strings, Dunlop Jazz III XL picks
Shure SM57 mic in front of the amp
Dont play after you bathe.
Ibanez SA160QM
Laney HCM10
Squier Bullet Strat
MXR Carbon Copy
Zoom Tri Metal
Modtone Flanger(mini)
Korg Pitchblack
Timtone acoustic
Dip your fingers in surgical alcohol or whatever it is, itll harden the skin. Thats what my mate does to the soles of his feet to help in intense rugby practise.

flickr you might
Quote by MrCarrot
Oranges are actually a revolution though - they're the next step from Rectos IMO.