I'm trying to learn how to play this. The tabs make it seem easy enough, and I can play it if I silence the individual strings according to the tab linked below. But when I look at John play, it looks like he's strumming all the chords instead of plucking the individual strings. Can anybody help me out on how he does this?

I'm going off of this tab. Riff starts on line 5
yeh when i play it i strum and mute all the other strings. it helps to have big hands but if you dont then just practice and you will eventually figure out a comfortable way to do it.
So to do this for "Can't stop" I'd have to be muting 5 of the strings since the riff only has one note that sounds out?