im using a VOX AD50VT
and im trying to get a decent southern rock or blues tone

anyone have any suggestions?

My Gear:
Gibson Explorer - Burgandy Finish
Fender Showmaster Orange/blacksunburst
Vox AD Valve Amp
Digitech Hot Head Distortion Pedal
Ernie Ball Strings
DR Black Beauty Strings
This is similar to what I like to use(have the same amp), but with more bass and a little chorus(that's just me). You could probably find what you're looking for by tweaking that preset, though.