lemon oil
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I've always used a lemon-oil based substance. NEVER USE A SILICONE BASED OIL.

from Muzique:

To clean a natural finish fretboard or neck, little is required in the way of chemical treatment. Basically you use a clean rag to remove as much of the dirt build-up as possible. Around the frets, grime often gets packed in and is very hard to remove. A plastic scrubbing pad is recommended since it will be softer and less likely to scratch, although very fine grades of steel wool (000 grade) may be used with care. Either type of scrubber should be plain; NO SOAP as is often in SOS pads or similar. Watch the steel wool because any fine bits of metal that are shed by the pad will be attracted by the magnets of guitar pickups.

A furniture oil may be placed on a clean rag and wiped around the hard to clean spots to assist the pad in removing the dirt. Once the fretboard is clean, wipe the entire surface with the oil dampened cloth to seal it. The furniture oil that is left behind will replenish the oil lost from the surface of the wood and help retard further losses. Use as little as possible; you just want to put a slight gloss on the surface.

Select a furniture oil that contains petroleum distillates. It is required by Federal law to have a child resistant cap and to state on the label: "Contains petroleum distillates. Harmful or fatal if swallowed". Lemon oil makes the product smell better and might add a little cleaning action due to its solvency, but is not required. Avoid silicones and waxes.

Buy a good quality furniture oil. Since you use it sparingly and only clean once or twice per year, a typical bottle will last a lifetime.

dunlop fretboard cleaner/conditioner. about $4 a bottle.

a couple times a year. and if you take off all the strings, make sure you know how to set up a guitar.

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if your gonna use lemon oil, make sure its PURE lemon oil.

over anything else though, id recommend gorgomyte(sp?). its the awesomest fretboard cleaning product iv ever come across.