Hey, I was using Guitar Pro 5 and I have a track in this song which uses a cello, it was working fine before but for some reason now the cello won't play, and neither will any other instruments which don't use RSE, can someone please help me?

Sometimes, if you use MIDI with other software, it won't work on GP anymore. Try restarting. Usually works.
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Failing that, click your volume control button in your taskbar, and look for the level that says SW Syntch, I think it is. If it's not up, turn it up.