Hello. I have an ibanex gio. An epiphone les paul and Vox AD50VT amp. Does anyone have any tips for a achieving an exellent metal tone.
High gain, bass and treble (not to 10 though)
mids down a little past the middle, not completely scooped.

If that fails, get a pedal.
Get an overdrive pedal...I have the AD30VT and its almost impossible to get a good modern metal tone out of the amp. I have a Digitech Bad Monkey pedal, and it fixed the problem.
get a pedal...

in my opinion/ experience valvatronix series die at high gain....
1957 Reissue Gibson Les Paul Custom [gone ]
1958 Reissue Sunburst (Ice Tea)
1959 Reissue Sunburst (Cherry)
Gibson Les Paul Studio
Epiphone SG
50th Anniversary CS Masterbuilt Strat

Fender Deluxe Reverb Reissue
Marshall JCM 2000 DSL
Get a MXR Zakk Wylde Overdrive pedal thats what i use and i have the same set up as u with a Gibson les paul and the vox. Also don't put the output all the way up on this pedal if u have the gain all the way up