whats the diff between f spaced and reg pups?

looking to upgrade on my new rg4exqm1

either Seymour Duncan TB4 bridge and SH1N neck pickups (don't know middle yet thinking maybe a lipstick tube for the heck of it)

or the evolution set by dimarzio

so deff need to know size and am taking opinions on the pups
My Rig...

2003 Ovation Collectors Series
Custom U.S.A. Parts Strat
Gibson SG Faded Special

Crate V50 112
Fender Sidekick Reverb 65

Boss CH-1
Boss CS-3
Boss DS-1
Boss NS-2
Original Crybaby