I wanted to play the song "Welcome Home" by Coheed and Cambria and I saw there are 4 guitars in it. If I wanted to play the Lead guitar which guitar should I chose? And would I be aloud to play guitar one with the guitar that is lead (he only plays beginning intro)? Thanks for your help

The "Welcome Home" Tab I am looking at is this one:

ok, so if I wanted to play lead I could play guitar one (intro only) and guitar 3?