Whenever I start Winamp, I get this error. It pops up a few times, but if I press cancel enough, Winamp eventually starts... this just started, so maybe it's something with a Winamp update?

are you running Windows 95???
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Have you tried putting a disk in the drive, then starting it, then opening a different playlist, then closing it, then taking the disk out and starting it again?

It has to be said - the new Winamp is total shite.