Not since decent FPS games have been out
Ibanez RG3270M Prestige
Gibson SG Standard
Fender Mexican Strat w/ Kinman Woodstock Pickups

Vox Valvetronix AD120VTX (soon to be a Peavey 6505)

Ibanez TS9 Tube Screamer
Dime Cry Baby From Hell
I used to. I played since I was like.. 8, and quit when I was 12 or so. Loved the game. Then guitar came into my life.. Eh, not really. Didn't pick up a guitar till I was 13.
I know exactly what I think I'm doing.