...BOSS ME-50 for Distortion / Overdrive?

I tried asking a few days ago, but got no replies; what're the best settings for an early Rage Against The Machine / Audioslave tone?

My favourite "pedals" on it are the DS2 and the Guv, but I can't get settings right without it sounding drowned out / suppressed, y'know?

So, whoever has a ME-50, help me out. :p
"Levelled up. Still no solos."