I have a Boss TU-2 tuner and i'm just wondering if i should put it in the guitar line or effects loop?
Put it very first, right after the guitar.
ESP LTD EC-256 and a Fender Deluxe VM
right after the guitar in the line not effects loop tuner before all other effects i find it best to go tuner wah phase 90 then my gain pedals but thats just me i dunno what u have but anything like a delay and stuff you might want to run through ur loop or at the end of the chain