how would you pick this lick? should i start on a up stroke or down stroke?? pplz tell me how you would do it

I wouldn't pick it, I'd legato that!
but i'm a legato style player
I'd pick the first two 7s on the 5th string, and the fives on the forth string, and then the seven on the 5th
so down up on the 7th fret and pull for the 5th fret, downstroke to hit the 5th fret on the 4th string, hammer the 7th on the fifth string and pick down up, on the 5th fret of the 4th string, tap the 7th fret of the fifth and pull off to the 5th fret
Out here you've gotta know where your towel is!