Would i have to make any major changes to a guitar if i put a left handed neck onto a right handed body?

Im wanting to make a guitar that's similar to this:


UG's Stock Market Guy

Hablo Español
Wǒ néng shuō Zhōngwén

So you can speak to me in English, Spanish or Chinese

My Recordings:

Dissident Blues
El Farol
We'll Make This Work
Stop This Train
Just change the nut, it will be cut upside down. Inonation and such would also need adjusted but otherwise should be ok
Quote by Zangetsu 101
Girl (Ned/chav) annoying me on the bus.

Me "Have you ever bled out your arse-hole?"

Her: Facial expression was priceless - "What??! Noo!"

Me: "Well if you want to keep it that way, **** off."

She then turned away and whimpered.
Also, I believe Warmoth makes necks with a reverse headstock, but with the side-dot markers on the correct side.