I will probably be getting a fender tube amp in the near future, and I would like to get all the tone I can from it, which means moving my Boss ME-50 out of my chain, although I still need it about 1/2 the time for effects. Would this work and preserve my tone?

Strat -->BOSS LS-2 -->BOSS RC-2 -->BOSS TU-2 -->Said amplifier

with the BOSS ME-50 in the effects loop of the LS-2

In this fashion, can I switch with the LS-2 between my ME-50 in the loop, and the unaffected guitar sound, and if so will this help the tone?