I'm looking to by a new amp. I'm leaning towards a Fender blues jr. or blues deluxe, but they don't have an effects out or loop feature. Will it make a difference in my sound if I use guitar pedals straight into the the amp, like a compressor, overdrive, delay, and wha?

Another question...If it does make a considerable difference, are there any combo amps you would suggest that I look at that have an and effects loop. Nothing big. From 5 - 50 watts. It's mainly for my home studio and local bars. The amp should be great for country and blues.