I got 11-50, and what is on my guitar now is a lighter gauge string, I really just wanna know if having the nut slotted matters, I didn't bother on my 1st guitar (I don't really care about it) but the guitar I have right now I love and wanna treat it right.
ESP Ltd EC100-Qm
Line 6 Spider III 75W
So I saw this in the wrong forum...

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wrong forum. but yes you should slot the nut. well not you, you will probly mess it up seeing as you messed up putting this in the right forum.
I'm not sure what kind of a nut you have on that 100-series, but my EC-1000 has an Earvana Compensated Nut, meaning that the slots are a lot wider than the strings.

But anyway 11-50 isn't too big, you should be just fine.
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It's caught me in its spotlight
Dancing in the moonlight
On this long hot summer night

Martin D-28