I play something along the lines of For The Fallen Dreams or Misery Signals style music, and I need to tighten up my sound.

The low end is kinda flabby sounding, and the mid and highs aren't defined.

I am using a B52 AT100 into a 212 cab. The pedals are a NS-2, SD-1, and GE-7.
Not to sound patronising, but why not turn the gain and bass down, and the presence and midrange up?
Are you boosting with the SD-1? What frequencies are you boosting/cutting with the EQ?