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Sign me up. Gonna go with Pain by Four Star Mary, easy guitar and vocals.
Came into this thread expecting Buffy.

Was disappointed.
Quote by Eggmond
I hate this ****ing hegemonic heteronormative cis straight white male patriarchal bullshit that rules society


Right on, non-gender specific sibling! Down with this sort of thing!
As opposed to trans majors/graduates? You have something against trans people?
When I was your age, for our graduation we got a degree, and we were grateful.
Recent studies have actually suggested that if those who regularly eat high fat/high sugar food only eat within an 8 hour period each day, rather than spread out over the whole 16 hours one is generally awake for, it would seriously reduce weight gain or even promote weight loss, depending on exact levels of fat and sugar, and amounts of exercise. Maybe if politicians a) listened to experts and took notice of new developments and b) focussed on educating people rather than banning things, there would be far less of a problem.
Quote by WCPhils
Plus the laugh track it horrendous.

My god, how I hate laugh tracks.


While I can't stop people from hating the show, can people please stop with this crap. Go on youtube and look up one of the behind the scenes shows they've done. You will quite clearly see that it's an audience, not a sodding laugh track. Track down all the people who were in the audience laughing and punch them in the face if you want, but at least get your facts straight.

Also, CSI: Miami's gone. Boo hoo. Sad face. Bright side, maybe there'll be funding available for more BBT. Or a Castle spin off featuring the character Adam Baldwin guest starred as.
"Puny god."

"Have you ever tried shawarma? There's a shawarma joint about two blocks from here. I don't know what it is, but I wanna try it."
Sign me up. I need to get out of a ridiculous rut anyways
Quote by CaptainAmerican

The fire brigade and the police force are not included when I talk about welfare or universal healthcare. I could talk about them but its for another thread maybe. Also your analogy doesnt take into account that I can voluntarily give people. My idea doesnt involve keeping all of the money to myself and watching the poor people starve. I have been held up by an armed robber a few times by the way, they usually dont want to shoot you.


On the voluntarily giving money to people point: that's fair, my analogy doesn't take that option into account (Although a tribe of hunters would generally have the tribal chief distribute the meat rather than have the killer distribute it, much like the goverment distributing taxpayers' money). And being willing to give money to charities for those less fortunate is commendable. However, having healthcare, housing and the like for poorer people handled entirely by independent charities is far too impractical. I'll not say that the current system is perfect, you only have to walk through Nottingham city centre at night to get an idea of the amounts of people that need help and get none. And yes, there are people who live on benefits when they are perfectly capable of work and are making no effort to find work. But the people who leech from the system are far outnumbered by those who actually have a disability, or who have qualifications and are trying to find work when there is so little work available, and need money to get by in the meantime. If the government were to transfer the responsibility for all of those people to independent charities, far more people would end up on the streets, because the charities wouldn't be able to handle as many of them as the government can. And those who scam from the system would stand even less chance of getting caught as the charities wouldn't have access to the data held by the police, department for work and pensions, transport department, etc which is used to catch these people. And that's not even taking into account the fact that far less people would voluntarily fund these charities.

Now, on the fire brigade/police point: I'm afraid it doesn't work like that. You don't get to choose what is a right and what is a privilege. I don't get why, if you think people should have to pay for their own healthcare, that you think people should have the fire brigade come and put out their burning house on taxpayers' money. Illness and house fires are both potentially deadly, so why should the government fund prevention of/stopping other people's houses burning down but not treating someone's brain tumour? Also you're a bit unclear (or I've missed where you clarified, if so, apologies) on whether you don't want to have to pay any tax at all (which is what I think you meant) or if you're fine having the goverment take some of your money for fire service, police, military, scientific research, and politicians/civil servants pay, just not as much as they take now and as long as none of it goes to welfare/health. While your initial post implies the former, the fact that you would still expect the government to provide fire and police services implies you would still be fine with paying some tax. This makes no sense. If you don't want to have to put money towards one essential service for those less fortunate, why don't you mind putting money towards others that are arguably less important (considering the number of fires that require the fire brigade to intervene and the number of crimes committed are less than the number of illnesses and injuries that the population suffers from, and that those who can't afford housing generally aren't at risk of their house being burgled or burning down)? When you start removing one service from the list of things that are so important that the Government needs to provide it for its citizens, where do you start?

(And on the armed robbery point, it was just an example which, even if the robber doesn't want to shoot, could still lead to injury or death. They bring loaded guns, that does risk them being forced to shoot or the gun accidentally going off. I could really have used an example of any violent crime or anything which would lead to loss of personal belongings).

Healthcare and welfare arent the only ways to help out poor people. There are a lot of other things that could help out those who are poor which I feel like the UK and the rest of Western European countries arent doing. As one example I dont think the government should set the minimum wage. There should be no minimum wage laws in my opinion.


OK, I'm going to try to remain civil here but it's kindof difficult. Please, just read this quote out loud to yourself. If you hear it out loud maybe you'll realise just how arse-backwards it is. You think that getting rid of minimum wage will mean that the government won't need to pay benefits? That is what leads to sweatshops paying their employees fifty pence for working a twelve-hour shift. It solves nothing and creates far worse problems. In a lot of jobs (e.g. waiters in restaurants, who generally make minimum wage), it won't lead to more people being employed, because the current number of employees gets all the required work done, it just leads to their current employees being paid less, and thus less people able to afford housing/food/healthcare. In industries such as the manufacturing industry, it leads to more people working, but most likely being paid less than they would make on the current benefits system (which currently pays jobseekers who do not pay rent £56 per week, the equivalent of 7-8 hours work at minimum wage). As it is, minimum wage or jobseekers' benefit can only support a person without a family, yet many people are trying to support families on minimum wage or jobseekers' allowance. Scrapping benefits and minimum wage will lead to even more people trying to support families on even less money, severely increasing the need for these charities which you think will be able to handle all of these poor people.

Sorry for the wall of text.
TS obviously doesn't understand the concept of a society, so here's some education. Think for a minute of a tribe of hunters. The hunters who make the kill don't keep all the meat for themselves, they share the meat with the weaker members of the tribe. If only the better hunters ate, the weaker members would die. Then the stronger members would not benefit from other skills that the weaker members perfected while the stronger members were out hunting, such as patching up wounds and making weapons. Inability to treat wounds or repair weapons would impair their ability to hunt, and they would die. Britain is this hunter tribe on a massive scale, and money has replaced meat. Sharing the money you bring in with the rest of society, through taxes, leads to benefit for yourself as well as those less fortunate. If you were to say to the Government "I will pay no taxes, and I will not accept any aid from you." then you may make more money at first, but you will not be treated in any NHS hospital in the event of injury or illness. No ambulance will come for you if you're hit by a car. If your house catches fire, the fire brigade will let it burn. You're held up by an armed robber, the police will let him shoot. Good luck surviving like that.
Since everyone is going on about how Axl or Izzy should have been there, I have to say:

Where was Tracii Guns?
Slash has said in his autobiography that he never felt that Gilby Clarke's playing fit with the band, but Axl forced the others to let him in.
Basically there's this astronaut called Major Tom. He's having a chat with Ground Control, at round about a hundred thousand miles away from Earth, when he decides his spaceship should navigate itself rather than he do the navigating. It goes out of control, Major Tom asks Ground Control to tell his wife that he loves her, and contact is lost.
Let's see if I can do better than last time:
Easy guitar - John Frusciante: Look On
Intermediate guitar - Jeff Beck: A Day In The Life
Quote by FryingNemo

George Lucas


Got to be the original model of the Millennium Falcon.

And I would totally steal Nathan Fillion's brown coat.

And, for shits and giggles, the 1 from the door of 10 Downing Street.
Quote by Kensai
If you look at the first paragraph I wrote you'll see that I would've agreed with you.


You did. I should clarify that I didn't mean that as disagreeing with your opinion so much as the overall view of western (probably eastern too though I'm not sure) culture, and was just using your example of Bond to illustrate my point.
Quote by Kensai
Basically, post pictures of characters you feel dress well. Not neccessarily formal or anything, just characters who you think always wear great outfits.

James Bond, of course, has been a fashion icon for decades. All Bonds (excluding Lazenby) have dressed with the handsomest suits of the contemoprary times.


I've never understood why "Well-dressed" automatically means "in a suit." Admittedly I'm not in a position to say that my style of dress is better (scruffy is kindof my look), but I don't get what's so great about suits. I've never seen a suit that looks anywhere near as awesome as what this dashing young gentleman is wearing



or for something more casual and less space train robbery-y

I am going to say this once, and once only.

The word you are looking for is "hypothesis"
Quote by niejel


You missed out my entry in easy, on page 4, just after random3's post with the link to his advanced entry
Here's my entry for easy http://profile.ultimate-guitar.com/Crofty89/music/all/play1095111

Recording quality isn't great and I really suck, but it's done.

My intermediate entry isn't happening.
Given up on Blackbird, it's a bit too ambitious a choice for me. Gonna try and record Rivers of Avalon tonight, doubt it will be much good though
Quote by IRISH_PUNK13
Tell me, how do you feel about garden gnomes?<________<


Generally indifferent. Do people of my personality type generally develop a hatred of or extreme love for garden gnomes?
Ta-dah, your personality type is INFP!
Introverted (I) 68% Extraverted (E) 32%
Intuitive (N) 55% Sensing (S) 45%
Feeling (F) 65% Thinking (T) 35%
Perceiving (P) 68% Judging (J) 32%


so INFP, but apparently not very committed to it.
Shout "I regret nothing"
Get hit by a hail of bullets
Whisper to someone close enough to hear my last words "The twenty million pounds is hidden in..."
Quote by IRISH_PUNK13
Exactly. It's almost as if life itself gives us cancer.


Well statistically speaking, the vast majority of people who died of cancer had lived. That correlation can't be coincidental.
Quote by Karaethon
It's all in Eb standard man! They don't change up the tuning at all!


The tab from Total Guitar magazine a few months back says that the intro and solos are in E standard and the verses and chorus are in Drop D.
Am I allowed to smoke a pipe and sip a glass of Bushmill's Irish whiskey if I join you by this fire?

I'd like to contribute a spot of UNKLE (if they're obscure enough). While they are still active today, they formed in the '90s making slow tempo electronica/trip hop with a number of guest vocalists including Richard Ashcroft (The Verve) and Ian Brown (The Stone Roses).
http://www.youtube.com/watch?v=RdgI1342CNM&feature=related
http://www.youtube.com/watch?v=gzJT0rElo0c

I'll also add some Seahorses, John Squire's short lived indie band from after The Stone Roses broke up, that got far less recognition than they deserved despite their relatively famous guitarist. The lyrics to their most famous single, Love Me and Leave Me, were supposedly written by Liam Gallagher. If that's true, then it makes you wonder what happened to him between then and when he started writing more lyrics for Oasis.

http://www.youtube.com/watch?v=gLhIw8_IK3U (not the official video as the only copy of that on youtube is a censored version that removes the religious references in the first few lines)
I'm on a boat, motherfukkers!
Quote by AdamDK
The second solo especially is pretty fast, I'll probably end up improvising bits of it.


I can see myself having the same problem with Blackbird when I start on the second solo.
While I'm doing better at Blackbird than I thought, I may have to cheat slightly on the intro and play it the same as the verse riff (they're pretty much the same except the verses don't use the bottom string). It's a bitch trying to play a song in which part was written in standard and part in drop D.
can our imagination play a role in this?

some people have "false" memories


Yes, it can. While imagination and abstract thought are still poorly understood in a biologica sense, it is known that neurons making up cognitive centres of the brain (areas of the cerebral cortex) can activate (or in some cases increase their level of activation, as a lot of neurons are constantly active) without any external stimulus. How these correspond to imagination I'm not entirely sure (not a psychologist), but as the areas that deal with memory (hippocampus and amygdala) don't recieve input directly from eyes, ears etc but recieve it after that input has been processed by the cerebral cortex (possibly other areas too, I'll have to check that) then there is nothing stopping memories being formed by activation of cognitive areas that originated within the brain. So yes, this process would be pretty much the same for memory of imagination/false memories, The input that reaches the areas that this process occurs is more or less the same regardless of source.

anyway i can only see this leading to the powers that be using it against people

Not really. The only possible use against people that this could have is by getting an enzyme into the entire brain that breaks down one or more components of this process. Even then it would be complete memory removal, which is a lot less practical for the government than just having the person that they need to keep quiet meet with a little accident.

I find it insulting that idiots like these propose that the information stored in our brain is as trivial as bits and bytes. The brain is the pinnacle of continuous signal processing - these digital analogies are embarrassing.


Well bits and bytes is a form that the layman can understand, as these days most people at least understand the basics of computer storage. Yes, it's dumbing it down, but on the other hand I'd rather a basic idea of things like this reached the public in a way that they would understand rather than science being something only for the people with PhDs and years of learning technical jargon. People are far too afraid of science (as the memory altering/the matrix/ghost in the shell posts in this thread prove) because even in the past century, where it has become more widely understood and accepted than in any other era of history, it is often not presented as something that the general public can understand. The past few decades have seen improvement, because people have started communicating science to the general public in a way that they can process and that interests them (for example by people such as Professor Brian Cox). If articles like this follow suit, showing the simplified version and telling the reader where more information can be found, it stops the public being scared of science and protesting against beneficial things such as GM crops and the MMR vaccine, because they can make informed opinions without the training scientists have, rather than assume it's bad because some reporter communicates their ill-informed opinion in a way the public can understand.
Quote by metal4eva_22


Now, my objections with this publication come from learning about microtubules in uni. We learned that microtubules are very dynamic structures. I find it hard to believe that such constantly changing proteins could store information for long periods of time. However I'm still doing my undergrad and by no means claim to be an expert on microtubules.

Here is a post from r/science that pretty much sunk the theory for me:


While my knowledge of microtubules is also limited (I'm a neuroscientist but my field is more related to the classical ion-channel mediated model described in the article you quoted, I'll get to that in a moment), from what I understand, the phosphorylation by the CAM kinase stabilises the structure, allowing them to bind to other structures for long periods which is how the information is stored.
Now onto the article you quoted:
There is a great, well-supported, theory of how memories are encoded in the brain called synaptic long-term potentiation. This theory says that memory in our brains is stored in the complex web of synapses that connect our network of neurons together. When we learn or forget something, some of those synapses get a bit stronger or weaker-that's where the information lives. There's good evidence that this is true e.g., this nobel prize winning line of work However, almost no one would make the outrageous claim that this explains all of memory, just that we know where the "atom" of memory lives-and it lives in the synapses.

Hameroff is proposing that this framework is wrong, and instead memory is stored at the sub-cellular level in microtubules (the neural skeleton). This is an extraordinary claim (it would mean among other things, that all of the electrical firing that happens in neurons, signifies nothing), for which is offered very ordinary evidence. The paper merely shows that there exists a microtubule protein that has multiple states and therefore could act as a switch. If you have switches you can store bits-but there's no evidence presented that any information is actually being stored, let alone that the information being stored has anything to do with memory.


The article in the OP, or Craddock's paper, don't claim that the previous theory is wrong, and the two theories are by no means mutually exclusive. I can't find Hammeroff's paper (a link would be helpful if you've got one) but I dount he claims that the theory is wrong or that electrical firing signifies nothing either. The first paragraph of that quote over-simplifies the synapse, meaning a reader who doesn't know further details wouldn't realise that the two theories can actually be two parts of the whole system.

The part of a nerve that recieves the signal at a synapse (the postsynaptic terminal) has a number of neurotransmitter receptors in its membrane. Some of these open ion channels, allowing positive ions (and thus electrical current) into the cell (called ionotropic receptors). Some of them activate a series of kinases similar to those described in the link in the OP (called metabotropic receptors). One neurotransmitter, called Glutamate, activates multiple types of both ionotropic and metabotropic receptors. The ionotropic glutamate receptors mediate the synaptic changes described in the quote (I'll not go into too much detail). The role of the metabotropic glutamate receptors is less well understood. But, as they activate kinase enzymes within the cell, and are themselves activated by the same transmitter as the ion channels previously thought to mediate memory formation, logically the CAM kinases and microtubules can be activated by the metabotropic receptors, and then regulate the action of the ionotropic receptors from within the cell (regulating synapses is mentioned as a function of the phosphorylated microtubules in the article).

It all fits together, just papers focus on one part of the process at a time, until the end, where they explain how their results could fit with previous knowledge. Then articles like this take only the main focus of the paper and you don't get the whole picture.


EDIT: on an unrelated note to the rest of this post, this does NOT mean we will be uploading consciousness into computers or robots. The Matrix and Ghost in the Shell will not become reality through this, and it will be useless for creating artificial intelligence. This does not mean artificial memories or memory wiping. We can't just put some CAM Kinase and microtubules into part of a circuit board. We can't just take the CAM kinases and microtubules out of your neurons and transfer them to a computer or another brain. To copy memories or create artificial ones the same cellular and tissue conditions would have to be reproduced to cause the molecules to behave that way. Each kinase and microtubule do not represent a specific memory, so these findings don't make copying or targeted deleting of memory possible.
^ That thought process gave us Machinedramon.

Just try and get your Mudkip anywhere near that in one piece.

Also
Agumon. It turned into an armoured cyborg T-rex that could fly. What's not to love?
The best comedy is in fact Ancient Greek. Aristophanes' The Acharnians and The Poet and the Women are still unparalleled.

/Extreme elitist
Quote by hey_guys553
pride and prejudice And Zombies
its off the hook, man.


Fix'd
Sign me up for easy and intermediate on guitar. Gonna go with Rivers of Avalon by Red Hot Chili Peppers for easy, and Blackbird by Alter Bridge for intermediate (as I'm feeling ambitious). Might enter one on ocarina too if I can think of something.
Really he should vote for this guy